Meditation and Mindfulness: Effectiveness and Safety
Evidence-based guide to meditation and mindfulness benefits, risks, and scientific research findings.

Meditation and mindfulness have become increasingly popular wellness practices in contemporary society, with millions of people seeking these techniques to improve their mental and physical health. These ancient practices, rooted in various cultural and spiritual traditions, have gained significant attention from the scientific and medical communities. The National Center for Complementary and Integrative Health (NCCIH) has invested considerable resources in researching the effectiveness and safety of these practices to provide evidence-based information to the public and healthcare providers.
Understanding the true benefits and potential risks of meditation and mindfulness requires examining rigorous scientific evidence. While these practices are generally considered safe for healthy individuals, it is important to recognize that like any intervention, they carry certain considerations and potential adverse effects that deserve attention and discussion.
Are Meditation and Mindfulness Practices Safe?
Meditation and mindfulness practices are generally considered to have few risks when practiced appropriately. However, the scientific literature on safety remains limited, as few comprehensive studies have thoroughly examined these practices for potentially harmful effects. This gap in research makes it difficult for health professionals to provide completely definitive statements about safety across all populations and practice variations.
A comprehensive 2020 review that examined 83 studies involving a total of 6,703 participants provided important insights into the frequency of negative experiences. The review found that 55 of the 83 studies reported negative experiences related to meditation practices. Based on this analysis, researchers concluded that approximately 8 percent of meditation participants experienced negative effects from their practice, a percentage comparable to that reported for psychological therapies. The most commonly reported negative effects were anxiety and depression, though the severity and duration of these experiences varied among participants.
When examining mindfulness-based stress reduction (MBSR) programs specifically, an analysis limited to three studies involving 521 participants found that the mindfulness practices were not more harmful than receiving no treatment at all. This finding suggests that while some individuals may experience adverse effects, mindfulness-based interventions do not appear to cause greater harm than the alternative of no intervention.
For generally healthy individuals who practice meditation under appropriate guidance, the practice is considered safe. However, individuals with certain medical conditions or those in special circumstances such as pregnancy should consult with healthcare providers before beginning meditation or mindfulness practices.
Effectiveness for Mental Health Conditions
Stress, Anxiety, and Depression
One of the most extensively researched applications of mindfulness and meditation is their effectiveness in treating anxiety and depression. A 2018 NCCIH-supported analysis of 142 groups of participants with diagnosed psychiatric disorders such as anxiety or depression examined mindfulness meditation approaches compared with no treatment and with established evidence-based treatments. This comprehensive analysis included more than 12,000 participants and found that for treating anxiety and depression, mindfulness-based approaches were more effective than no treatment at all. Importantly, these approaches worked as well as established evidence-based therapies such as cognitive behavioral therapy and antidepressant medications.
A 2021 analysis of 23 studies involving 1,815 participants examined mindfulness-based practices used as treatment for adults with diagnosed anxiety disorders. The studies in this analysis compared mindfulness-based interventions (whether used alone or in combination with usual treatments) with other treatments including cognitive behavioral therapy, psychoeducation, and relaxation techniques. The analysis showed mixed results for the short-term effectiveness of different mindfulness-based approaches. Overall, these approaches were more effective than usual treatments at reducing the severity of anxiety and depression symptoms, though only some types of mindfulness approaches were as effective as cognitive behavioral therapy.
Important limitations must be considered when interpreting these findings. The risk of bias for all the studies examined was unclear, and the few studies that followed up with participants for periods longer than two months found no long-term effects of the mindfulness-based practices. This suggests that while mindfulness can provide short-term benefits for anxiety and depression, the durability of these benefits requires further investigation.
Post-Traumatic Stress Disorder
A 2018 review supported by NCCIH examined the effects of meditation and other mindfulness-based practices on symptoms of post-traumatic stress disorder (PTSD). The review included eight studies examining these approaches, with study participants including veterans, nurses, and people who experienced interpersonal violence. Six of the eight studies reported that participants had a reduction of PTSD symptoms after receiving some form of mindfulness-based treatment, suggesting potential benefits for this challenging condition.
Effectiveness for Pain Management
Pain management represents another significant area where meditation and mindfulness have been extensively studied. The research findings in this area demonstrate the potential of these practices as complementary approaches to conventional pain management.
Chronic Pain and Low-Back Pain
A 2020 report by the Agency for Healthcare Research and Quality concluded that mindfulness-based stress reduction was associated with short-term (less than six months) improvement in low-back pain but not fibromyalgia pain. This distinction is important, as it suggests that mindfulness may be particularly beneficial for certain types of pain conditions.
A 2017 analysis of 30 studies involving 2,561 participants found that mindfulness meditation was more effective at decreasing chronic pain than several other forms of treatment. However, it is important to note that the studies examined were of relatively low quality, which limits the strength of conclusions that can be drawn from this analysis.
A 2020 NCCIH-supported analysis of five studies of adults using opioids for acute or chronic pain, with a total of 514 participants, found that meditation practices were strongly associated with pain reduction. This finding is particularly significant given the ongoing challenges with opioid use and the potential for mindfulness to serve as a complementary pain management approach.
Headaches
A 2019 review found that mindfulness-based approaches did not reduce the frequency, length, or pain intensity of headaches. However, the authors noted that their results are likely imprecise because only five studies involving a total of 185 participants were included in the analysis. Any conclusions made from this analysis should therefore be considered preliminary, and further research is needed to definitively establish whether mindfulness interventions can benefit people suffering from headaches.
Effectiveness for Sleep and Insomnia
Insomnia and poor sleep quality are common problems affecting millions of people worldwide. Mindfulness meditation practices may help address these issues by promoting relaxation and reducing the racing thoughts that often accompany sleep difficulties.
A 2019 analysis of 18 studies involving 1,654 total participants found that mindfulness meditation practices improved sleep quality more than education-based treatments. However, the effects of mindfulness meditation approaches on sleep quality were no different than those of evidence-based treatments such as cognitive behavioral therapy and exercise. This suggests that while mindfulness can be an effective tool for improving sleep, it is one of several evidence-based approaches available to individuals struggling with sleep issues.
Effectiveness for Substance Use and Relapse Prevention
A 2017 analysis specifically focused on Mindfulness-Based Relapse Prevention (MBRP) examined nine studies involving 901 total participants of this approach. The analysis concluded that MBRP was not more effective at preventing substance use relapses than other treatments such as health education and cognitive behavioral therapy. However, MBRP did slightly reduce cravings and symptoms of withdrawal associated with alcohol use disorders, suggesting potential benefits for individuals struggling with substance use issues even if complete relapse prevention is not achieved.
Other Potential Benefits
Beyond the major conditions discussed above, meditation and mindfulness have been studied for various other health conditions. Research suggests these practices may help with irritable bowel syndrome (IBS), where an 8-week mindfulness meditation program reduced symptom severity in a trial of 75 women. Additionally, meditation practices such as Transcendental Meditation may help lower blood pressure in individuals at increased risk of developing hypertension, though more research is needed to confirm these findings.
How Mindfulness Meditation Works
Understanding the mechanisms by which mindfulness meditation produces its effects is an important area of ongoing research. Recent neuroimaging studies have provided insights into how these practices affect the brain.
Research has shown that mindfulness meditation and placebo employ different neural pathways to reduce pain. In mindfulness meditation, participants are typically taught to focus on changing the cadence of their breath and to refocus on their breath when distracted. They are also taught to reduce self-judgment by acknowledging without reaction their arising thoughts, feelings, and emotions. This deliberate attentional training appears to activate specific brain regions in response to pain that differ from the neural patterns activated by placebo effects.
A notable finding from NCCIH-funded research indicates that mindfulness meditation helps control pain without relying on the brain’s naturally occurring opiates. This suggests that combining mindfulness with pain medications and other approaches that rely on the brain’s opioid activity may be particularly effective for reducing pain.
NCCIH-Funded Research Initiatives
The National Center for Complementary and Integrative Health continues to support a variety of meditation and mindfulness studies to expand our understanding of these practices. Current research initiatives include:
- An evaluation of how the brain responds to the use of mindfulness meditation as part of a combined treatment for migraine pain
- A study of the effectiveness of mindfulness therapy and medication (buprenorphine) as a treatment for opioid use disorder
- A study of a mindfulness training program designed to help law enforcement officers improve their mental health by managing stress and increasing resilience
- Investigation of meditation for teens experiencing chronic, widespread pain, such as from fibromyalgia
- Research on stress reduction for people with multiple sclerosis
- Studies examining mindfulness meditation for post-traumatic stress disorder, headaches, and blood pressure reduction
Key Considerations for Practice
While meditation and mindfulness practices are generally safe, certain considerations should be kept in mind. Mind and body practices generally have good safety records when done properly by a trained professional or taught by a well-qualified instructor. However, just because a practice is safe for most people does not necessarily mean it is safe for every individual. Medical conditions or special circumstances such as pregnancy may affect the safety of a mind and body practice for particular individuals.
Individuals interested in beginning meditation or mindfulness practices should consider consulting with healthcare providers, particularly if they have diagnosed psychiatric conditions, chronic pain, sleep disorders, or other medical concerns. This consultation can help ensure that these practices are appropriate for their individual circumstances and can be integrated safely with any other treatments they may be receiving.
Frequently Asked Questions
Q: Are meditation and mindfulness the same thing?
A: While related, meditation and mindfulness are not identical. Mindfulness is the practice of maintaining moment-to-moment awareness without judgment, while meditation is a broader term that can encompass various techniques aimed at achieving mental clarity and relaxation. Mindfulness can be a form of meditation, but meditation can also include other practices such as Transcendental Meditation or breathing exercises.
Q: How long does it take to experience benefits from meditation?
A: The timeline for experiencing benefits varies among individuals and depends on the specific benefit being sought. Some research suggests that benefits can be observed after 8 weeks of regular practice, though some people may notice improvements in stress or sleep more quickly. Consistency and proper instruction are important factors in achieving benefits.
Q: Can meditation replace conventional medical treatments?
A: No, meditation and mindfulness should not replace conventional medical treatments for serious health conditions. Rather, these practices are most effective when used as complementary approaches alongside evidence-based medical care. Individuals should continue taking prescribed medications and following their healthcare provider’s recommendations while potentially adding meditation as a complementary practice.
Q: Are there any groups for whom meditation is not recommended?
A: While meditation is generally safe, individuals with certain psychiatric conditions, severe trauma, or specific medical conditions should consult with healthcare providers before beginning practice. Additionally, some individuals may experience adverse effects including anxiety or depression, and these experiences should be discussed with a healthcare provider.
Q: What is the evidence for meditation’s safety in long-term practice?
A: While short-term safety is well-established, fewer studies have examined long-term safety and effects. Meditation is generally considered safe for healthy people when practiced appropriately, but more research is needed to fully understand long-term effects and any potential adverse outcomes with extended practice.
Q: Can children practice meditation and mindfulness?
A: Yes, children can practice meditation and mindfulness, and research suggests these practices may be beneficial for stress reduction in younger populations. However, techniques should be age-appropriate, and instruction should be provided by qualified practitioners familiar with teaching children.
References
- Meditation and Mindfulness: Effectiveness and Safety — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2024. https://www.nccih.nih.gov/health/meditation-and-mindfulness-effectiveness-and-safety
- Mindfulness Meditation and Placebo Modulate Different Brain Patterns to Reduce Pain — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2024. https://www.nccih.nih.gov/research/research-results/mindfulness-meditation-and-placebo-modulate-different-brain-patterns-to-reduce-pain
- Mind and Body Approaches for Stress and Anxiety — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2024. https://www.nccih.nih.gov/health/providers/digest/mind-and-body-approaches-for-stress-science
- 8 Things to Know About Meditation and Mindfulness — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2024. https://www.nccih.nih.gov/health/tips/8-things-to-know-about-meditation-and-mindfulness
- Mind and Body Practices — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2024. https://www.nccih.nih.gov/health/mind-and-body-practices
- Meditation — National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health. 2016. https://files.nccih.nih.gov/s3fs-public/Meditation_04-25-2016.pdf
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